This is a one day seminar that describes the technological state-of-the-art of non relational database and in-memory computing with a special focus on trend setter SAP HANA. This is not a promotional presentation in favour of or against SAP HANA. It is a neutral report on what the technology behind SAP HANA is and how it relates to evolution of database engine design and to offerings of competitors. In the second part in dives deeper into technology details of SAP HANA and works out what condition should be met to have a benefit from SAP HANA and what measures and effort are needed to replace an existing database with SAP HANA.